Kenneth T. He

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About Me

I am Kenneth He, who is a freshman at Wake Forest University.   I'd love to share some of the interesting events in my activities with you.   I have been a swimmer for approximate 9 years and have devoted most of my spare time in the sport.   You may find some of my happy moments with my good friends on the site.

Born in Durham, NC         I was born at Duke Children's Hospital & Health Center in Durham, NC.   I have an elder sister and both of us grew up in Chapel Hill, NC.

School         I am attending Wake Forest University.   I am a member of the swim team and a core member for our team.

PROJECTS [top]

1. Developing a Tool for Reverse Complement DNA Sequences     After having learned Java programming language in the past semester, I have developed a standalone and Web-based tool for reverse complement DNA sequences.   For more details, please click here.

2. Predicting SARS-CoV-2 3D Structure     Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that causes respiratory illness in humans.   It was first reported in December 2019 in an outbreak occurring in Wuhan, China.  It is still spreading and affecting humans' working environment & life styles worldwide.  Predicting its trimer 3D structure can be helpful in developing reliable vaccine and/or targeted therapies.        Since the spring of 2022, I got started to setup an AlphaFold2 running platform on my workstation with GPUs, on which I used to play games.   With help from my dad, I have set AlphaFold2 up on my workstation and have run a number of tests for predicting protein structures based on their amino acid (AA) sequences.   AlphaFold2 is an AI system developed by Google DeepMind that predicts a protein or complex's 3D structure from its AA sequence.  It regularly achieves accuracy competitive with experiment.   With the current ongoing virus of COVID-19/SARS-CoV-2, I have decided to work on this specific strand of protein and be able to estimate what it looks like. Using this application, I can visualize the SARS-CoV-2 structure and export different types of images including surface, sphere and cartoon.   The protein of SARS-CoV-2 is a trimer.  We can distinguish the three distinct strands through different colors to display these proteins using a program called PyMOL.